Several fabrics are used in industries for making bedsheets like cotton, Synthetics, Microfiber, Silk, and Linen. Each material consists of different properties, providing a variety of options to people. The opinion of the best fabric will differ from person to person. Their place of residence will also help determine the best material for bed sheets. Cotton, however, is the most popular fabric for making bedsheets worldwide. It is soft, easy to care for and very comfortable, and available at a much reasonable rate. However, silk mattresses are the most comfortable and luxurious of all but are way too costly, and that\'s why not preferred much.